BONINE (meclizine) is an H 1 histamine receptor blocker of the piperazine side chain group. It exhibits its action by an effect on the Central Nervous System (CNS), possibly by its ability to block muscarinic receptors in the brain.


BONINE is effective in the management of nausea, vomiting and dizziness associated with motion sickness.


Do not take this product, unless directed by a doctor, if you have a breathing problem such as emphysema or chronic bronchitis, or if you have glaucoma or difficulty in urination due to enlargement of the prostate gland.

May cause drowsiness; alcohol, sedatives and tranquilizers may increase the drowsiness effect. Avoid alcoholic beverages while taking this product. Do not take this product if you are taking sedatives or tranquilizers without first consulting your doctor. Do not drive or operate dangerous machinery while taking this medication.

Usage In Children

Clinical studies establishing safety and effectiveness in children have not been done; therefore, usage is not recommended in children under 12 years of age.

Usage in Pregnancy

As with any drug, if you are pregnant or nursing a baby, seek advice of a health care professional before taking this product.


Drowsiness, dry mouth, and on rare occasions, blurred vision have been reported.


For motion sickness, take one or two tablets of Bonine once daily, one hour before travel starts, for up to 24 hours of protection against motion sickness. The tablet can be chewed with or without water or swallowed whole with water. Thereafter, the dose may be repeated every 24 hours for the duration of the travel.


BONINE (meclizine HCl) is available in convenient packets of 8 and 16 chewable tablets of 25 mg. meclizine HCl.


NOTE: These photos can be used only for identification by shape, color, and imprint. They do not depict actual or relative size.

The product samples shown here have been supplied by the manufacturer and reproduced in full color by PDR as a quick-reference identification aid. While every effort has been made to assure accurate reproduction, please remember that any visual identification should be considered preliminary. In cases of poisoning or suspected overdosage, the drug' identity should be verified by chemical analysis.



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